The emerging field of senotherapeutic drugs

Future Med Chem. 2018 Oct;10(20):2369-2372. doi: 10.4155/fmc-2018-0234. Epub 2018 Oct 16.
No abstract available

Keywords: BCL-2; NF-κB; PI3K/Akt; cellular senescence; dasatinib; drug repurposing; metformin; natural products; quercetin; senescence-associated secretory phenotype; senolytics; senomorphics; target-based drug discovery.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cellular Senescence / drug effects*
  • Drug Discovery
  • Humans
  • Nervous System Diseases / drug therapy*
  • Nervous System Diseases / pathology*
  • Small Molecule Libraries / chemistry
  • Small Molecule Libraries / pharmacology*

Substances

  • Small Molecule Libraries