Protective effect of tea against lead and cadmium-induced oxidative stress-a review

Biometals. 2018 Dec;31(6):909-926. doi: 10.1007/s10534-018-0153-z. Epub 2018 Oct 13.

Abstract

Exposure to Cd and Pb reduces the activity of antioxidant enzymes, which points to a decrease in the antioxidant potential of the body as a result of supplying factors which enhance cellular oxidation processes. Man is exposed to the effects of toxic metals because they are present in the environment, including in food. Since no effective ways to reduce the concentrations of Cd an Pb in food exist, studies are undertaken to develop methods of reducing their toxic effect on the body through chelating these metals using nutrients (which reduces their absorption by tissues) or increasing the oxidative capacity of the body (which decreases the possibility of inducing oxidative damage to internal organs). Studies performed on laboratory animals have shown that the use of tea infusions fulfil both functions.

Keywords: Antioxidants; Cadmium; Lead; Oxidative stress; Protective effect; Tea.

Publication types

  • Review

MeSH terms

  • Animals
  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Cadmium / pharmacology
  • Humans
  • Lead / pharmacology
  • Oxidative Stress / drug effects*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Protective Agents / chemistry
  • Protective Agents / pharmacology*
  • Tea / chemistry*

Substances

  • Antioxidants
  • Plant Extracts
  • Protective Agents
  • Tea
  • Cadmium
  • Lead