Assessment of drug related problems among type 2 diabetes mellitus patients with hypertension in Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia

BMC Res Notes. 2018 Oct 12;11(1):728. doi: 10.1186/s13104-018-3838-z.

Abstract

Objective: This study was conducted to assess magnitude and pattern of drug related problems among patients with type 2 diabetes mellitus (T2DM) and hypertension.

Results: This study identified 364 drug related problems (DRPs) across the three categories of drug related problems, giving an average of 1.8 DRPs per patient. The effect of drug treatment being not optimal 179 (49.2%), untreated indication and symptoms 77 (21.1%), unnecessary drug-treatment 39 (10.7%) and adverse drug reactions 69 (19%) were the most frequent categories of DRPs identified. In general, high prevalence of drug-related problems was identified among patients with T2DM hypertension. The effect of drug treatment being not optimal, untreated indication and symptoms, unnecessary drug-treatment and adverse drug reactions were the most frequent categories of drug related problems identified. Therefore, the clinicians should work to improve patient care through prevention and resolving drug related problems since it can affect the quality of the care significantly.

Keywords: Drug related problems; Hypertension; Type 2 diabetic mellitus.

MeSH terms

  • Adult
  • Antihypertensive Agents / adverse effects*
  • Comorbidity
  • Diabetes Complications / drug therapy*
  • Diabetes Complications / epidemiology
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Drug-Related Side Effects and Adverse Reactions / epidemiology
  • Drug-Related Side Effects and Adverse Reactions / etiology*
  • Ethiopia / epidemiology
  • Female
  • Hospitals, University
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / epidemiology
  • Hypoglycemic Agents / adverse effects*
  • Male
  • Middle Aged

Substances

  • Antihypertensive Agents
  • Hypoglycemic Agents