Neuroblastoma and Histone Demethylation

N Engl J Med. 2018 Oct 11;379(15):1476-1477. doi: 10.1056/NEJMcibr1806782.

Authors

Steven G DuBois¹, Julie R Park¹

Affiliation

¹ From the Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston (S.G.D.); and the Department of Pediatrics, Seattle Children's Hospital and University of Washington School of Medicine, Seattle (J.R.P.).

PMID: 30304660
DOI: 10.1056/NEJMcibr1806782

No abstract available

MeSH terms

Animals
Benzazepines / pharmacology*
Benzazepines / therapeutic use
Cell Line, Tumor
Child
Demethylation / drug effects*
Gene Expression
Histones / antagonists & inhibitors*
Histones / metabolism
Humans
Jumonji Domain-Containing Histone Demethylases / antagonists & inhibitors
Models, Animal
Neuroblastoma / drug therapy*
Neuroblastoma / genetics
Neuroblastoma / metabolism
Pyrimidines / pharmacology*
Pyrimidines / therapeutic use

Substances

Benzazepines
GSK-J4
Histones
Pyrimidines
Jumonji Domain-Containing Histone Demethylases