Knowledge translation of clinical practice guidelines among neurologists: A mixed-methods study

PLoS One. 2018 Oct 10;13(10):e0205280. doi: 10.1371/journal.pone.0205280. eCollection 2018.

Abstract

Objectives: Clinical practice guidelines have the potential to improve care, but are often not optimally implemented. Improving guideline use in clinical practice may improve care. The objective of this study was to identify the barriers and facilitators (determinants) of guidelines use among neurologists and to propose a strategy to improve guideline implementation.

Methods: This was a mixed-methods study design. A quantitative, population-based, cross-sectional survey of Canadian neurologists was conducted. Associations between guidelines use and determinants of guidelines use were examined. Focus groups and interviews were conducted using purposeful sampling of the population. Determinants of guideline use were mapped to interventions to establish a strategy for guideline implementation among neurologists.

Results: 38.7% (n = 311) of neurologists responded to the survey. Typically, respondents had been practicing for 16.6 years and worked in an academic institution in an urban setting. Being male and having an academic affiliation was associated with guideline use. Determinants of guideline use differed between guideline users and non-users; non-users consistently rating determinants lower than users, especially applicability. Two focus groups and one interview (n = 11) identified six main themes of determinants of guideline use: Credibility, knowledge, applicability, resources, motivation, and target audience; which was congruent with the quantitative data. The proposed knowledge translation strategy contains three pillars: guidelines development, dissemination, and interventions.

Conclusions: Several determinants of guideline use not commonly discussed in the literature were identified (applicability, target audience, credibility). The proposed implementation strategy is a valuable resource for guideline developers and policy/decision-makers to improve knowledge translation of guidelines among neurologists.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Attitude of Health Personnel*
  • Canada
  • Cross-Sectional Studies
  • Evaluation Studies as Topic
  • Female
  • Focus Groups
  • Guideline Adherence / statistics & numerical data*
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Male
  • Motivation
  • Neurologists / psychology*
  • Practice Guidelines as Topic*
  • Research Design

Grants and funding

This study was funded in part by a University of Calgary Thesis Research Grant (file 1033705) and salary support was provided to KM Sauro by an Alberta Innovates: Health Solutions graduate scholarship. S Wiebe was the holder of the Hopewell Professorship for Clinical Neurosciences Research at the Hotchkiss Brain Institute, University of Calgary. H Quan’s salary was supported by an Alberta Innovates: Health Solutions population health scholar award. N Jetté was the holder of a Canada Research Chair Tier 2 in Neurological Health Services Research. There was no additional external funding received for this study. The funders played no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.