Assessment of perioperative surgical complications in pediatric kidney transplantation: A comparison of pre-emptive and post-dialysis recipients

Abstract

Purpose: To determine whether there is a benefit to pre-emptive kidney transplantation in reducing surgical complications in pediatric population.

Methods: A retrospective review of kidney transplantations in our institution from 2000 to 2015 was performed. Intra- and postoperative complication rates and one-year graft survival were compared in their respective donor type groups (pre-emptive DD vs post-dialysis DD; pre-emptive LD vs post-dialysis LD).

Results: A total of 318 patients were identified (pre-emptive DD, n = 21; post-dialysis DD, n = 145; pre-emptive LD, n = 54; post-dialysis LD, n = 98). Between the DD groups, post-dialysis DD group was more likely to be female (P = 0.017). There was no difference in rates of intraoperative complications or graft loss (P = 0.365 and 1.000, respectively). Post-dialysis DD groups were more likely to have postoperative complications (9.5% vs 35.1%, P = 0.023), but no difference in complications with Clavien-Dindo grade 3 or higher was found (P = 0.130). Between the LD groups, post-dialysis LD group was more likely to be females (P = 0.017) and with intrinsic renal (non-urological/structural) ESRD etiology (P = 0.003). There was no difference in rates of intra-and postoperative complications or graft loss (P = 0.353, P = 0.605, and P = 0.616, respectively).

Conclusions: Overall, there are similar perioperative complication rates between pediatric pre-emptive and post-dialysis kidney transplant recipients.

Keywords: complications; kidney transplantation; post-dialysis; pre-emptive.