Piezoelectric Biomaterials for Sensors and Actuators

Meysam T Chorsi; Eli J Curry; Hamid T Chorsi; Ritopa Das; Jeffrey Baroody; Prashant K Purohit; Horea Ilies; Thanh D Nguyen

doi:10.1002/adma.201802084

Piezoelectric Biomaterials for Sensors and Actuators

Adv Mater. 2019 Jan;31(1):e1802084. doi: 10.1002/adma.201802084. Epub 2018 Oct 8.

Authors

Meysam T Chorsi¹, Eli J Curry², Hamid T Chorsi³, Ritopa Das², Jeffrey Baroody², Prashant K Purohit⁴, Horea Ilies¹, Thanh D Nguyen^{1

2

5

6}

Affiliations

¹ Department of Mechanical Engineering, University of Connecticut, Storrs, CT, 06269, USA.
² Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269, USA.
³ Department of Electrical & Computer Engineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA.
⁴ Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, PA, 19104, USA.
⁵ Institute of Materials Science, University of Connecticut, Storrs, CT, 06269, USA.
⁶ Institute for Regenerative Engineering, University of Connecticut Health Center, Farmington, CT, 06030, USA.

PMID: 30294947
DOI: 10.1002/adma.201802084

Abstract

Recent advances in materials, manufacturing, biotechnology, and microelectromechanical systems (MEMS) have fostered many exciting biosensors and bioactuators that are based on biocompatible piezoelectric materials. These biodevices can be safely integrated with biological systems for applications such as sensing biological forces, stimulating tissue growth and healing, as well as diagnosing medical problems. Herein, the principles, applications, future opportunities, and challenges of piezoelectric biomaterials for medical uses are reviewed thoroughly. Modern piezoelectric biosensors/bioactuators are developed with new materials and advanced methods in microfabrication/encapsulation to avoid the toxicity of conventional lead-based piezoelectric materials. Intriguingly, some piezoelectric materials are biodegradable in nature, which eliminates the need for invasive implant extraction. Together, these advancements in the field of piezoelectric materials and microsystems can spark a new age in the field of medicine.

Keywords: bioactuators; biodevices; biomaterials; biosensors; piezoelectricity.

Publication types

Review

MeSH terms

Biocompatible Materials / chemistry*
Biocompatible Materials / metabolism
Biosensing Techniques / instrumentation
Biosensing Techniques / methods*
Electricity
Inorganic Chemicals / chemistry
Micro-Electrical-Mechanical Systems
Monitoring, Physiologic / instrumentation
Monitoring, Physiologic / methods
Organic Chemicals / chemistry
Tissue Engineering

Substances

Biocompatible Materials
Inorganic Chemicals
Organic Chemicals