[The clinical analysis of diabetic patients with chronic inflammatory demyelinating polyradiculoneuropathy]

Zhonghua Nei Ke Za Zhi. 2018 Oct 1;57(10):749-752. doi: 10.3760/cma.j.issn.0578-1426.2018.10.010.
[Article in Chinese]

Abstract

To explore clinical characteristics, electrophysiological findings and treatment response in diabetic patients with chronic inflammatory demyelinating polyradiculoneuropathy (DM-CIDP). Thirty-six CIDP patients were identified, 10 were DM-CIDP and 26 were non-DM-CIDP. Clinical medical records, electrophysiological data and treatment were retrospectively reviewed. DM-CIDP patients were significantly older than non-DM-CIDP patients [(56.7±10.0) years old vs. (40.4±16.9) years old, P=0.001]. However, clinical characteristics and abnormalities of electrophysiological tests in both groups were comparable. DM-CIDP subjects responded to corticosteroids or intravenous immunoglobulin, thus with better prognosis.

探讨糖尿病合并慢性炎性脱髓鞘性多发性神经根神经病(DM-CIDP)的临床特点、神经电生理特点及治疗。收集北京大学第三医院36例慢性炎性脱髓鞘性多发性神经根神经病(CIDP)患者的临床资料,包括神经电生理及治疗情况等,其中10例为DM-CIDP,占全部CIDP患者的27.8%。DM-CIDP组患者年龄显著高于无糖尿病合并症的CIDP(NDM-CIDP)组患者[(56.7±10.0)岁比(40.4±16.9)岁,P=0.001]。DM-CIDP和NDM-CIDP组患者其他临床特点、神经电生理各项检查未见明显差异。DM-CIDP患者主要采用糖皮质激素或丙种球蛋白等治疗,预后均较好。.

Keywords: Chronic inflammatory demyelinating polyradiculoneuropathy; Diabetes mellitus.

MeSH terms

  • Adrenal Cortex Hormones
  • Adult
  • Aged
  • China / epidemiology
  • Diabetes Mellitus / epidemiology*
  • Diabetic Neuropathies / diagnosis
  • Diabetic Neuropathies / epidemiology*
  • Humans
  • Middle Aged
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / epidemiology*
  • Prognosis
  • Retrospective Studies
  • Young Adult

Substances

  • Adrenal Cortex Hormones