Association of neighbourhood socioeconomic status and diabetes burden using electronic health records in Madrid (Spain): the HeartHealthyHoods study

BMJ Open. 2018 Oct 4;8(9):e021143. doi: 10.1136/bmjopen-2017-021143.

Abstract

Objective: To study the association between neighbourhood socioeconomic status and diabetes prevalence, incidence, and control in the entire population of northeastern Madrid, Spain.

Setting: Electronic health records of the primary-care system in four districts of Madrid (Spain).

Participants: 269 942 people aged 40 or older, followed from 2013 to 2014.

Exposure: Neighbourhoodsocioeconomic status (NSES), measured using a composite index of seven indicators from four domains of education, wealth, occupation and living conditions.

Primary outcome measures: Diagnosis of diabetes based on ICPC-2 codes and glycated haemoglobin (HbA1c %).

Results: In regression analyses adjusted by age and sex and compared with individuals living in low NSES neighbourhoods, men living in medium and high NSES neighbourhoods had 10% (95% CI: 6% to 15%) and 29% (95% CI: 25% to 32%) lower prevalence of diabetes, while women had 27% (95% CI: 23% to 30%) and 50% (95% CI: 47% to 52%) lower prevalence of diabetes. Moreover, the hazard of diabetes in men living in medium and high NSES neighbourhoods was 13% (95% CI: 1% to 23%) and 20% (95% CI: 9% to 29%) lower, while the hazard of diabetes in women living in medium and high NSES neighbourhoods was 17% (95% CI: 3% to 29%) and 31% (95% CI: 20% to 41%) lower. Individuals living in medium and high SES neighbourhoods had 8% (95% CI: 2% to 15%) and 15% (95% CI: 9% to 21%) lower prevalence of lack of diabetes control, and a decrease in average HbA1c % of 0.05 (95% CI: 0.01 to 0.10) and 0.11 (95% CI: 0.06 to 0.15).

Conclusions: Diabetes prevalence, incidence and lack of control increased with decreasing NSES in a southern European city. Future studies should provide mechanistic insights and targets for intervention to address this health inequity.

Keywords: diabetes; neighborhoods; record linkage; social epidemiology; social inequalities; spain.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cohort Studies
  • Diabetes Mellitus / blood*
  • Diabetes Mellitus / epidemiology*
  • Electronic Health Records
  • Female
  • Glycated Hemoglobin / metabolism
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prevalence
  • Residence Characteristics*
  • Sex Factors
  • Socioeconomic Factors*
  • Spain / epidemiology

Substances

  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human