Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping

Zhiqiang Yan; Yuqian Wang; Yanli Nie; Xu Zhi; Xiaohui Zhu; Meng Qin; Shuo Guan; Yixin Ren; Ying Kuo; Di Chang; Wei Chen; Peng Yuan; Liying Yan; Jie Qiao

doi:10.1016/j.jgg.2018.05.006

Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping

J Genet Genomics. 2018 Sep 20;45(9):505-508. doi: 10.1016/j.jgg.2018.05.006. Epub 2018 Jul 11.

Authors

Zhiqiang Yan¹, Yuqian Wang², Yanli Nie², Xu Zhi², Xiaohui Zhu², Meng Qin², Shuo Guan², Yixin Ren², Ying Kuo², Di Chang², Wei Chen¹, Peng Yuan², Liying Yan³, Jie Qiao⁴

Affiliations

¹ Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing 100191, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
² Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing 100191, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, Beijing 100191, China.
³ Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing 100191, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, Beijing 100191, China. Electronic address: yanliyingkind@aliyun.com.
⁴ Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing 100191, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, Beijing 100191, China; Beijing Advanced Innovation Center for Genomics (ICG), Peking University, Beijing 100871, China. Electronic address: jie.qiao@263.net.

PMID: 30287172
DOI: 10.1016/j.jgg.2018.05.006

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Blastocyst / physiology*
Female
Genetic Carrier Screening / methods*
Haplotypes*
Humans
Male
Polymorphism, Single Nucleotide
Pregnancy
Preimplantation Diagnosis / methods*
Sperm Injections, Intracytoplasmic
Spermatozoa / physiology
Translocation, Genetic / genetics*