Neurosurgical Management of Spastic Conditions of the Upper Extremity

Hand Clin. 2018 Nov;34(4):547-554. doi: 10.1016/j.hcl.2018.06.012. Epub 2018 Aug 18.

Abstract

Spasticity is a hypertonic segmental reflex pathway caused by a central nervous system injury. Spasticity of the upper extremity causes loss of function, joint contracture, pain, and poor cosmesis. Treatment aims to reduce or change the pathophysiology underlying the hyperactive reflex from dorsal sensory rootlets through the intrinsic machinery of the spinal cord to the neuromuscular junction. There are many treatments for upper extremity spasticity including oral medication, physiotherapy, intrathecal baclofen, and lesional or neuromodulatory surgical approaches. Goals of treatment must always be clearly defined, but neurosurgical management is most effective when paired with multidisciplinary therapies and caregiver participation.

Keywords: Baclofen therapy; Movement disorder; Neuromodulation; Spasticity; Upper extremity.

Publication types

  • Review

MeSH terms

  • Baclofen / therapeutic use
  • Humans
  • Infusion Pumps, Implantable
  • Muscle Relaxants, Central / therapeutic use
  • Muscle Spasticity / physiopathology
  • Muscle Spasticity / therapy*
  • Neurosurgical Procedures*
  • Upper Extremity / physiopathology
  • Upper Extremity / surgery*

Substances

  • Muscle Relaxants, Central
  • Baclofen