Khan and colleagues demonstrate how serial blood-based liquid biopsies integrated with imaging and mathematical modeling can accurately "forecast" the time to treatment failure in patients with metastatic colorectal cancer treated with EGFR blockade, by early detection of molecular alterations associated with drug resistance in cell-free DNA. Cancer Discov; 8(10); 1213-5. ©2018 AACR See related article by Khan et al., p. 1270.
©2018 American Association for Cancer Research.