Massive false-positive gene-gene interactions by Rothman's additive model

Ann Rheum Dis. 2019 Mar;78(3):437-439. doi: 10.1136/annrheumdis-2018-214297. Epub 2018 Sep 29.

Author

Affiliation

¹ Department of Biology, Kyung Hee University, Seoul 02447, South Korea kkim@khu.ac.kr.

PMID: 30269053
DOI: 10.1136/annrheumdis-2018-214297

No abstract available

Keywords: ant-CCP; gene polymorphism; rheumatoid arthritis.

Publication types

Letter
Research Support, Non-U.S. Gov't
Validation Study

MeSH terms

Adult
Anti-Citrullinated Protein Antibodies / analysis
Anti-Citrullinated Protein Antibodies / genetics
Arthritis, Rheumatoid / diagnosis*
Arthritis, Rheumatoid / genetics
Arthritis, Rheumatoid / immunology
Autoantibodies / analysis*
Autoantibodies / genetics
Epistasis, Genetic*
False Positive Reactions
Female
Genetic Testing / methods
Genetic Testing / statistics & numerical data*
Genome-Wide Association Study
Humans
Male
Models, Theoretical*
Reproducibility of Results
Risk Assessment / methods
Risk Assessment / statistics & numerical data
Risk Factors

Substances

Anti-Citrullinated Protein Antibodies
Autoantibodies