Porous Co3O4 nanosheets as a high-performance non-enzymatic sensor for glucose detection

Anal Bioanal Chem. 2018 Nov;410(29):7663-7670. doi: 10.1007/s00216-018-1380-4. Epub 2018 Sep 28.

Abstract

Novel porous Co3O4 nanosheets (NSs) were synthesized on the flexible carbon cloth (CC) substrate by a facile hydrothermal method and applied to construct a non-enzymatic sensor for glucose detection. The sensor is based on the electro-catalytic oxidation of glucose on the surface of Co3O4 NSs. Since this particular nanostructure can provide large surface area and more active sites, the Co3O4 NSs non-enzymatic sensor exhibits excellent analytical performance, such as a high sensitivity (8506 μA mM-1 cm-2), a fast response time (less than 6 s), low detection limit of 1 μM, good selectivity, and long-term stability. The results suggest that the porous Co3O4 NSs have great potential applications in the development of sensors for enzyme-free detection of glucose.

Keywords: Co3O4 nanosheets; Glucose; High sensitivity; Non-enzymatic sensor.

MeSH terms

  • Biosensing Techniques / methods*
  • Cobalt / chemistry*
  • Glucose / analysis*
  • Glucose / chemistry
  • Limit of Detection
  • Nanostructures / chemistry*
  • Porosity

Substances

  • Cobalt
  • Glucose