Clinical trial recruitment of adult African American smokers from economically disadvantaged urban communities

J Ethn Subst Abuse. 2020 Jan-Mar;19(1):133-150. doi: 10.1080/15332640.2018.1489746. Epub 2018 Sep 28.

Abstract

This investigation evaluated the effectiveness and challenges of multiple recruitment methods, described as proactive, reactive, and combination methods, among adult African American smokers (N = 527) from economically disadvantaged urban communities enrolled to test progressively reduced nicotine content investigational cigarettes. The study evaluated success using descriptive statistics to measure the volume of phone calls and percentage of eligible participants per method. Reactive and combination strategies effectively prompted participants to call about the study. Combination methods yielded the highest eligibility rates. Findings demonstrate the unique recruitment successes within this population across a range of recruitment methods and may inform improved methods to recruit and engage African Americans in clinical trials.

Keywords: African Americans; clinical trial; economically disadvantaged; minority research recruitment; reduced nicotine cigarettes; smoking; tobacco regulation.

Publication types

  • Clinical Trial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Black or African American / statistics & numerical data*
  • Cigarette Smoking / therapy*
  • Clinical Trials as Topic / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nicotine / administration & dosage
  • Nicotinic Agonists / administration & dosage
  • Patient Selection*
  • Poverty / statistics & numerical data*
  • Process Assessment, Health Care*
  • Tobacco Products*
  • Tobacco Use Disorder / therapy*
  • Urban Population / statistics & numerical data*
  • Vulnerable Populations
  • Young Adult

Substances

  • Nicotinic Agonists
  • Nicotine