Usefulness of indocyanine green-fluorescence imaging for real-time visualization of pancreas neuroendocrine tumor and cystic neoplasm

J Surg Oncol. 2018 Nov;118(6):1012-1020. doi: 10.1002/jso.25231. Epub 2018 Sep 27.

Abstract

We evaluated the usefulness of fluorescence imaging using indocyanine green to identify pancreas tumors in 23 patients undergoing pancreas resection. This technique was useful in visualizing pancreas lesions during surgery, specifically, neuroendocrine tumors as fluorescence and cystic neoplasms as a fluorescence defect.

Keywords: fluorescence imaging (FI); indocyanine green (ICG); neuroendocrine tumor (NET); pancreas cystic neoplasm; pancreas lesion; pancreas resection.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Pancreatic Ductal / blood supply
  • Carcinoma, Pancreatic Ductal / diagnostic imaging
  • Carcinoma, Pancreatic Ductal / pathology
  • Carcinoma, Pancreatic Ductal / surgery
  • Coloring Agents
  • Female
  • Humans
  • Indocyanine Green*
  • Male
  • Middle Aged
  • Neuroendocrine Tumors / blood supply
  • Neuroendocrine Tumors / diagnostic imaging*
  • Neuroendocrine Tumors / pathology
  • Neuroendocrine Tumors / surgery*
  • Optical Imaging / methods*
  • Pancreatic Cyst / blood supply
  • Pancreatic Cyst / diagnostic imaging*
  • Pancreatic Cyst / pathology
  • Pancreatic Cyst / surgery*
  • Pancreatic Neoplasms / blood supply
  • Pancreatic Neoplasms / diagnostic imaging*
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / surgery*
  • Young Adult

Substances

  • Coloring Agents
  • Indocyanine Green