Abstract
The incidence of cervical carcinoma, which had been induced by vaginal application of inactivated herpes simplex virus type 2 (HSV-2) with 20% croton oil, was significantly reduced in mice prevaccinated with the Skinner herpes vaccine. There was evidence of an immunological response in both vaccinated and unvaccinated mice.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Viral / biosynthesis
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Croton Oil / toxicity
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Female
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Herpes Genitalis / complications
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Herpes Genitalis / prevention & control*
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Mice
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Simplexvirus / immunology*
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Uterine Cervical Neoplasms / etiology
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Uterine Cervical Neoplasms / pathology
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Uterine Cervical Neoplasms / prevention & control*
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Viral Vaccines / therapeutic use*
Substances
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Antibodies, Viral
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Viral Vaccines
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Croton Oil