Correlation between drinking water fluoride and TSH hormone by ANNs and ANFIS

Zohreh Kheradpisheh; Amir Hossein Mahvi; Masoud Mirzaei; Mehdi Mokhtari; Reyhane Azizi; Hossein Fallahzadeh; Mohammad Hassan Ehrampoush

doi:10.1007/s40201-018-0290-x

Correlation between drinking water fluoride and TSH hormone by ANNs and ANFIS

J Environ Health Sci Eng. 2018 Apr 11;16(1):11-18. doi: 10.1007/s40201-018-0290-x. eCollection 2018 Jun.

Authors

Zohreh Kheradpisheh¹, Amir Hossein Mahvi^{2

3}, Masoud Mirzaei⁴, Mehdi Mokhtari¹, Reyhane Azizi⁵, Hossein Fallahzadeh⁶, Mohammad Hassan Ehrampoush¹

Affiliations

¹ 1Environmental Science and Technology Research Center, Department of Environmental Health Engineering, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
² 2School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
³ 3Center for Solid Waste Research, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran.
⁴ 4Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁵ 5Department of Endocrinology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁶ 6Department of Biostatistics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Abstract

Background: Artificial neural networks (ANNs) and adaptive neural-fuzzy Inference system (ANFIS) are the best solutions to finding the correlation between some water parameters and human hormones. The correlation between thyroid stimulating hormone (TSH) and drinking water fluoride studied by ANN_S and ANFIS models in Yazd city.

Method: In this study, eighty people with thyroid gland disorder and 213 healthy people invited. Their thyroid hormones and fluoride drinking water analyzed.

Results: The result of ANFIS showed R² = 0.81 for test and R² = 0.85 for train in all cases and controls data. This results were R² = 0.73 and R² = 0.81 for ANNs respectively.

Conclusion: This models can be used as an alternative for show correlation between Drinking Water Fluoride and TSH Hormone and R² = 0.85 gained from ANFIS was the best.

Keywords: Adaptive neural-fuzzy inference system (ANFIS); Artificial neural networks (ANNS); Drinking water; Fluoride; Thyroid stimulating hormone (TSH).