An Occupational Legacy: Malignant Mesothelioma Incidence and Mortality in Wisconsin

J Occup Environ Med. 2018 Dec;60(12):1143-1149. doi: 10.1097/JOM.0000000000001461.

Abstract

Objectives: The aim of the study was to describe mesothelioma occurrence in Wisconsin from 1997 to 2013 by usual industry and occupation (I&O), including occupations generally considered low risk.

Methods: Population-based rates and standardized incidence and mortality ratios were calculated. Two case-control analyses were designed to compare mesothelioma incidence and mortality in specific I&O groups with occurrence of (1) brain and central nervous system cancers and (2) other causes of death, using logistic regression.

Results: Mesothelioma incidence and mortality were elevated in Wisconsin (SIRadj = 1.20 [1.13 to 1.28]; SMRadj = 1.30 [1.22 to 1.38]). Certain industry (construction, manufacturing) and occupation (construction and extraction) groups were associated with increased odds of mesothelioma, with some evidence of increased risk among teachers.

Conclusions: Forty years after the Occupational and Safety Health Act, mesothelioma incidence and mortality remain elevated in Wisconsin, with increased risk continuing for certain I&O groups.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Asbestos
  • Case-Control Studies
  • Construction Industry / statistics & numerical data
  • Death Certificates
  • Extraction and Processing Industry / statistics & numerical data
  • Female
  • Humans
  • Incidence
  • Industry / statistics & numerical data*
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / mortality
  • Male
  • Manufacturing Industry / statistics & numerical data
  • Mesothelioma / epidemiology*
  • Mesothelioma / mortality
  • Mesothelioma, Malignant
  • Middle Aged
  • Occupational Diseases / epidemiology*
  • Occupational Diseases / mortality
  • Occupational Exposure / statistics & numerical data*
  • Peritoneal Neoplasms / epidemiology*
  • Peritoneal Neoplasms / mortality
  • Pleural Neoplasms / epidemiology*
  • Pleural Neoplasms / mortality
  • Registries
  • Schools
  • Teaching / statistics & numerical data
  • Wisconsin / epidemiology
  • Young Adult

Substances

  • Asbestos