Mass spectrometry analysis of the diversity of Aβ peptides: difficulties and future perspectives for AD biomarker discovery

Expert Rev Proteomics. 2018 Oct;15(10):773-775. doi: 10.1080/14789450.2018.1525296. Epub 2018 Sep 26.

Authors

Natalia V Zakharova^{1

2}, Anna E Bugrova², Alexey S Kononikhin^{1

3}, Maria I Indeykina^{1

2}, Igor A Popov^{1

3}, Eugene N Nikolaev^{1

3

4}

Affiliations

¹ a Moscow Institute of Physics and Technology , Laboratory of ion and molecular physics , Moscow , Russia.
² b Emanuel Institute for Biochemical Physics , Russian Academy of Sciences , Moscow , Russia.
³ c V.L. Talrose Institute for Energy Problems of Chemical Physics , Russian Academy of Sciences , Moscow , Russia.
⁴ d Skolkovo Institute of Science and Technology , Center of Life Sciences , Moscow , Russia.

PMID: 30253669
DOI: 10.1080/14789450.2018.1525296

No abstract available

Keywords: Alzheimer’s disease; Amyloid; Aβ peptides; mass spectrometry; post-translational modifications.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Review

MeSH terms

Alzheimer Disease / blood*
Alzheimer Disease / cerebrospinal fluid
Amyloid beta-Peptides / blood*
Amyloid beta-Peptides / cerebrospinal fluid
Amyloid beta-Peptides / chemistry
Biomarkers / blood
Biomarkers / cerebrospinal fluid
Humans
Mass Spectrometry / methods*
Mass Spectrometry / trends
Molecular Diagnostic Techniques / methods*
Molecular Diagnostic Techniques / trends

Substances

Amyloid beta-Peptides
Biomarkers