Ocular Pemphigoid

Excerpt

Ocular cicatricial pemphigoid (OCP) is a form of mucous membrane pemphigoid (MMP) that features a chronic, relapsing-remitting bilateral conjunctivitis. Ultimately, patients affected by this autoimmune disease will experience conjunctival cicatrization or scarring, and if unresponsive to treatment or left untreated will develop corneal opacification and permanent vision loss. MMP can also affect the skin as well as mucous membranes of the mouth, nose, esophagus, genitals, and anus – causing erosions, blisters, and strictures. Ocular cicatricial pemphigoid represents about 60% to 70% of those affected by MMP.