Objective: To summarize the research progress of biocompatibility and surface modification of nickel titanium shape memory alloys (Ni-Ti SMA).
Methods: The relative researches about Ni-Ti SMA at home and abroad were reviewed, collated, analyzed, and summarized.
Results: At present, Ni-Ti SMA as an internal fixation material has been widely used in clinic. It has the following advantages: the super elasticity, the shape memory characteristic, the good wear resistance, and the strong corrosion resistance. It also can effectively avoid the internal fixator rupture caused by stress shielding. After surface modification, the biocompatibility of Ni-Ti SMA has been improved.
Conclusion: The Ni-Ti SMA is the most promising alloy material for the long-term internal fixator because of its excellent material properties.
目的: 总结镍钛形状记忆合金（nickel titanium shape memory alloys，Ni-Ti SMA）生物相容性及其表面改性的研究进展。.
方法: 广泛查阅国内外 Ni-Ti SMA 研究的相关文献，并进行整理、分析和总结。.
结果: 目前 Ni-Ti SMA 作为内固定材料，已广泛应用于临床，其具有超弹性、形状记忆特性、较好的耐磨性、较强的抗腐蚀性，能有效避免应力遮挡导致的内固定物断裂。Ni-Ti SMA 经过表面改性后，其生物相容性可得到改善。.
结论: Ni-Ti SMA 因具有优良的材料特性，成为非常有潜力的制备体内长期内植物的合金材料。.
Keywords: Nickel titanium shape memory alloys; biocampatibility; surface modification.