Viral Anti-CRISPR Tactics: No Success without Sacrifice

Michiel van Gent; Michaela U Gack

doi:10.1016/j.immuni.2018.08.023

Viral Anti-CRISPR Tactics: No Success without Sacrifice

Immunity. 2018 Sep 18;49(3):391-393. doi: 10.1016/j.immuni.2018.08.023.

Authors

Michiel van Gent¹, Michaela U Gack²

Affiliations

¹ Department of Microbiology, The University of Chicago, Chicago, IL 60637, USA.
² Department of Microbiology, The University of Chicago, Chicago, IL 60637, USA. Electronic address: mgack@uchicago.edu.

PMID: 30231980
DOI: 10.1016/j.immuni.2018.08.023

Abstract

Co-evolution with their bacterial hosts has led to viral countermeasures against CRISPR-mediated immunity. In a recent issue of Cell, Landsberger et al. (2018) and Borges et al. (2018) report that cooperation among bacteriophages and multiple infection events are necessary to overcome CRISPR immune responses.

Publication types

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MeSH terms

Bacteria / genetics
Bacteriophages / genetics*
Clustered Regularly Interspaced Short Palindromic Repeats*