Recent advances in the synthesis of cyclopropanes

Org Biomol Chem. 2018 Oct 17;16(40):7315-7329. doi: 10.1039/c8ob01187g.

Abstract

Cyclopropanes, one of the most important strained rings, have gained much attention for more than a century because of their interesting and unique reactivity. They not only exist in many natural products, but have also been widely used in the fields of organic synthesis, medicinal chemistry and materials science as versatile building blocks. Based on the sustainable development in this area, this review mainly focuses on the recent advances in the synthesis of cyclopropanes classified by the type of catalytic system, including regio-, diastereo-, and enantio-selective reactions.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't