Translational molecular imaging in exocrine pancreatic cancer

Eur J Nucl Med Mol Imaging. 2018 Dec;45(13):2442-2455. doi: 10.1007/s00259-018-4146-5. Epub 2018 Sep 17.

Abstract

Effective treatment for pancreatic cancer remains challenging, particularly the treatment of pancreatic ductal adenocarcinoma (PDAC), which makes up more than 95% of all pancreatic cancers. Late diagnosis and failure of chemotherapy and radiotherapy are all too common, and many patients die soon after diagnosis. Here, we make the case for the increased use of molecular imaging in PDAC preclinical research and in patient management.

Keywords: Molecular imaging; PET; Pancreatic ductal adenocarcinoma; Preclinical developments; SPECT.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Molecular Imaging / methods*
  • Pancreas, Exocrine / diagnostic imaging*
  • Pancreatic Neoplasms / diagnostic imaging*
  • Translational Research, Biomedical