Operated descending thoracic and thoracoabdominal atherosclerotic aortic aneurysm prognosis

J Med Vasc. 2018 Sep;43(5):288-292. doi: 10.1016/j.jdmv.2018.07.001. Epub 2018 Aug 4.

Abstract

Background: The long-term survival of patients treated from descending thoracic aneurysm (DTA) is well known, more than those treated from a thoracoabdominal aortic aneurysm (TAAA). Moreover, studies are rarely focused on the aneurysmal etiology and include both degenerative and post dissecting aneurysms. The aim of this study is to compare the long-term survival of patients operated from DTA or TAAA due to degenerative atherosclerosis.

Methods: Thirty-nine atherosclerotic aneurysm patients were operated between January 2007 and July 2015 at Rouen University Hospital. Eighteen DTA patients were operated by TEVAR and 21 TAAA patients (8 type I and 13 type III) by open approach. The main endpoint was remote survival patients.

Results: Overall, the initial population was similar in the two groups. However, one third of DTA were treated in context of emergency for painful aneurysm versus 9.5% of patients with TAAA (P=0.066). Survival median of 18 DTA was 18 months (1-68). Survival median of 21 TAAA followed was 66 months (1-91). Survival in both groups was statistically different with the log-rank test (P=0.044).

Conclusions: Long-term prognosis of atherosclerotic DTA may be worse than that of TAAA's. This retrospective study reflects experience in the management of DTA and TAAA in a single-center. Prospective data in patients treated with endovascular procedures for DTA or TAAA, with fenesterated or branched endoprosthesis, are warranted to confirm these results.

Keywords: Anévrisme aortique athéromateux; Anévrisme thoracique descendant; Anévrisme thoraco-abdominal; Aortic aneurysm; Aortic surgery; Atherosclerosis; Chirurgie ouverte; Classifications; Courbe de survie; Survival analysis; Traitement endovasculaire.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Aged
  • Aortic Aneurysm, Thoracic / etiology
  • Aortic Aneurysm, Thoracic / mortality*
  • Aortic Aneurysm, Thoracic / surgery*
  • Atherosclerosis / complications
  • Atherosclerosis / mortality*
  • Atherosclerosis / surgery*
  • Female
  • Humans
  • Male
  • Prognosis
  • Retrospective Studies
  • Survival Rate