Predictive accuracy of partial coherence interferometry and swept-source optical coherence tomography for intraocular lens power calculation

Sci Rep. 2018 Sep 13;8(1):13732. doi: 10.1038/s41598-018-32246-z.

Abstract

The purpose of this study is to compare the predictive accuracy of intraocular lens (IOL) calculations made with partial coherence interferometry (PCI, IOLMaster, version 5) and swept-source optical coherence tomography (SS-OCT, Argos). Axial length (AL), mean keratometry value (K), and anterior chamber depth (ACD) were obtained using PCI and SS-OCT optical biometers. Intraocular lens (IOL) power calculations were made using the Barret-Universal II, Haigis, Hoffer Q, SRK/T, and T2 formulas and compared the predictive accuracy between biometers. In 153 eyes (153 patients), axial length measurements made with PCI (24.65 ± 2.35 mm) and SS-OCT (24.62 ± 2.29 mm) were significantly different (P < 0.001). Corneal power (P = 0.97) and anterior chamber depth (P = 0.51) were not significantly different between biometer. The mean absolute error was not significantly different between the five IOL power calculation formulas for either PCI or SS-OCT measurements. When AL was 24.5-26.0 mm, mean absolute error derived from SS-OCT was smaller than mean absolute error derived from PCI for all five IOL power calculation formulas (all P < 0.05). In conclusion, predictive accuracy of PCI and SS-OCT were nearly the same. However, in medium-long eyes, the predictive accuracy of SS-OCT for IOL calculations was higher.