Terpenoids from Marine Soft Coral of the Genus Lemnalia: Chemistry and Biological Activities

Qihao Wu; Jiadong Sun; Jianwei Chen; Huawei Zhang; Yue-Wei Guo; Hong Wang

doi:10.3390/md16090320

Terpenoids from Marine Soft Coral of the Genus Lemnalia: Chemistry and Biological Activities

Mar Drugs. 2018 Sep 9;16(9):320. doi: 10.3390/md16090320.

Authors

Qihao Wu^{1

2}, Jiadong Sun³, Jianwei Chen⁴, Huawei Zhang⁵, Yue-Wei Guo^{6

7}, Hong Wang⁸

Affiliations

¹ College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. qihaowu@zjut.edu.cn.
² State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China. qihaowu@zjut.edu.cn.
³ Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD 20878, USA. sunjiadong@gmail.com.
⁴ College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. cjw983617@zjut.edu.cn.
⁵ College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. hwzhang@zjut.edu.cn.
⁶ College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. ywguo@simm.ac.cn.
⁷ State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China. ywguo@simm.ac.cn.
⁸ College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. hongw@zjut.edu.cn.

Abstract

Lemnalia is one of the most widely-distributed marine soft coral in tropical oceans and is known to produce novel terpenoids with a broad spectrum of biological activities. This review provides the first comprehensive overview of terpenoids produced by soft coral Lemnalia since their first discovery in 1974.

Keywords: Lemnalia sp.; bioactivity; marine soft coral; secondary metabolites.

Publication types

Review

MeSH terms

Animals
Anthozoa / genetics
Anthozoa / metabolism*
Anthozoa / microbiology
Anti-Inflammatory Agents / chemistry
Anti-Inflammatory Agents / isolation & purification
Anti-Inflammatory Agents / metabolism
Anti-Inflammatory Agents / pharmacology*
Antineoplastic Agents / chemistry
Antineoplastic Agents / isolation & purification
Antineoplastic Agents / metabolism
Antineoplastic Agents / pharmacology*
Biological Products / chemistry
Biological Products / isolation & purification
Biological Products / metabolism
Biological Products / pharmacology*
Biosynthetic Pathways / genetics
Cell Line, Tumor / drug effects
Humans
Molecular Structure
Oceans and Seas
Symbiosis
Terpenes / chemistry
Terpenes / isolation & purification
Terpenes / metabolism
Terpenes / pharmacology*

Substances

Anti-Inflammatory Agents
Antineoplastic Agents
Biological Products
Terpenes

Abstract

Publication types

MeSH terms

Substances

Grants and funding