Objective: To report a new case of prostatic carcinosarcoma, an uncommon and locally and distance aggressive tumor.
Method: We analyzed one case diagnosed in our Center, from clinical and pathological diagnosis to death, describing the treatments received.
Result: Patient presented a huge pelvic mass and a pulmonary metastasis that was treated with cystoprostatectomy and bilateral cutaneous ureterostomy with the diagnosis of carcinosarcoma of the prostate. He received 8 cycles of Docetaxel with bone progression and then 3 cycles of doxorubicin, suspending treatment due to progression. The survival was 18 months.
Conclusions: Prostate carcinosarcoma is a very aggressive neoplasia that does not respond to the usual treatments of prostate cancer.