Smart Bandages: The Future of Wound Care

Trends Biotechnol. 2018 Dec;36(12):1259-1274. doi: 10.1016/j.tibtech.2018.07.007. Epub 2018 Sep 6.

Abstract

Chronic non-healing wounds are major healthcare challenges that affect a noticeable number of people; they exert a severe financial burden and are the leading cause of limb amputation. Although chronic wounds are locked in a persisting inflamed state, they are dynamic and proper therapy requires identifying abnormalities, administering proper drugs and growth factors, and modulating the conditions of the environment. In this review article, we discuss technologies that have been developed to actively monitor the wound environment. We also highlight drug delivery tools that have been integrated with bandages to facilitate precise temporal and spatial control over drug release and review automated or semi-automated systems that can respond to the wound environment.

Keywords: drug delivery; flexible electronics; integrated systems; smart bandages; wound care.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Bandages / trends*
  • Chronic Disease
  • Drug Delivery Systems / methods*
  • Humans
  • Wound Healing
  • Wounds and Injuries / therapy*