A coumarin based highly sensitive fluorescent chemosensor for selective detection of zinc ion

Mohammad Zareh Jonaghani; Hassan Zali-Boeini; Hassan Moradi

doi:10.1016/j.saa.2018.08.061

A coumarin based highly sensitive fluorescent chemosensor for selective detection of zinc ion

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jan 15:207:16-22. doi: 10.1016/j.saa.2018.08.061. Epub 2018 Aug 30.

Authors

Mohammad Zareh Jonaghani¹, Hassan Zali-Boeini², Hassan Moradi¹

Affiliations

¹ Department of Chemistry, University of Isfahan, 81746-73441 Isfahan, Iran.
² Department of Chemistry, University of Isfahan, 81746-73441 Isfahan, Iran. Electronic address: h.zali@chem.ui.ac.ir.

PMID: 30195181
DOI: 10.1016/j.saa.2018.08.061

Abstract

A very effective and highly sensitive fluorescent chemosensor, based on 4-hydroxycoumarin skeleton substituted by benzothiazole moiety was synthesized and investigated for the detection of zinc ion. This chemosensor displays highly selective and sensitive fluorescence enhancement to Zn²⁺ over other metal ions examined in solution and in biological systems. The detection limit for the fluorescent chemosensor 1 toward Zn²⁺ was 3.58 × 10^-8 M. A simple and efficient approach was improved for the synthesis of chemosensor 1 starting from 4-hydroxycoumarin.

Keywords: Benzothiazole; Chemosensor; Coumarin; Fluorescent; Zinc ion.