[SIGNALING PATHWAYS INVOLVED IN THE REGULATION OF PROTEIN METABOLISM IN SKELETAL MUSCLE]

Abstract

The ability of muscle cells to respond to certain signaling molecules depends on the presence of specific proteins-receptors, ion channels and transporters, which create a system of metabolic inputs. All cells in the human body have a transmembrane signaling system that allows to get information from extracellular stimuli such as hormones, neurotransmitters, proteins, peptides, derivatives of amino acids and fat acids, sensor molecules. The results of researches published in the last two years, which expand knowledge of action of various factors on protein metabolism in skeletal muscles are presented in the review. The main attention is turned to the discovery and expansion of signaling pathways involved in the regulation of protein metabolism in skeletal muscle in different functional states of the person.