Rapid Therapeutic Response of Eosinophilic Meningoencephalitis in a Toddler With Baylisascaris procyonis Infection

WMJ. 2018 Aug;117(3):130-132.

Abstract

Introduction: Eosinophilic meningitis is an infrequently encountered condition. Baylisascaris procyonis (raccoon roundworm) infection, rarely diagnosed in North America, is a known cause of eosinophilic meningitis, often producing death or permanent neurologic damage.

Case report: We recently encountered a toddler with geophagia and probable exposure to raccoon feces, who presented with eosinophilic meningitis and encephalitis, and was diagnosed with B procyonis infection and possible Toxocara co-infection. His marked peripheral eosinophilia and neurologic symptoms rapidly responded to corticosteroid and albendazole therapy.

Discussion: Since B procyonis infection is infrequently encountered, its diagnosis in the proper clinical and epidemiologic setting may not always be considered, resulting in a delay of appropriate therapy. Our patient, diagnosed and treated early in his course, demonstrated rapid clinical and laboratory improvement with anti-inflammatory and antiparasitic therapy.

Conclusion: In cases of eosinophilic meningitis, infection with B procyonis should be routinely considered to allow timely institution of effective therapy for this unusual but potentially fatal or debilitating infection.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Albendazole / therapeutic use
  • Animals
  • Anthelmintics / therapeutic use
  • Ascaridida Infections / complications*
  • Ascaridida Infections / diagnosis*
  • Ascaridida Infections / drug therapy
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Humans
  • Infant
  • Male
  • Meningoencephalitis / drug therapy
  • Meningoencephalitis / parasitology*
  • Raccoons

Substances

  • Adrenal Cortex Hormones
  • Anthelmintics
  • Albendazole