Biallelic inactivation of the retinoblastoma gene results in transformation of chronic myelomonocytic leukemia to a blastic plasmacytoid dendritic cell neoplasm: shared clonal origins of two aggressive neoplasms

Blood Cancer J. 2018 Aug 22;8(9):82. doi: 10.1038/s41408-018-0120-5.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Biopsy
  • Bone Marrow / metabolism
  • Cell Transformation, Neoplastic / genetics*
  • Clonal Evolution
  • Dendritic Cells / metabolism*
  • Dendritic Cells / pathology*
  • Disease Progression
  • Exome Sequencing
  • Gene Silencing
  • Genes, Retinoblastoma*
  • Histiocytic Disorders, Malignant / genetics*
  • Histiocytic Disorders, Malignant / metabolism*
  • Humans
  • Leukemia, Myelomonocytic, Chronic / genetics*
  • Leukemia, Myelomonocytic, Chronic / pathology*
  • Male
  • Middle Aged