Updates in Primary Bone Tumors: Current Challenges and New Opportunities in Cytopathology

Abstract

The review summarizes the current diagnostic challenges in fine-needle aspiration of primary bone tumors, with focus on the application of new molecular and immunohistochemical techniques in the diagnosis of giant cell-rich neoplasms, chondrosarcomas, and notochordal tumors.

Keywords: Aneurysmal bone cyst; Chondroblastoma; Chondrosarcoma; Chordoma; Fine-needle aspiration; Giant cell tumor of bone; Giant cell–rich; Notochordal tumors.