The explosion of new methods in science has put additional pressure on authors, readers, and peer reviewers to evaluate the rigor and reproducibility of these new approaches. This issue brings together a collection of articles aimed to stimulate our thinking about how to evaluate the quality of these new methodologies, in the form of several expert reviews on domains ranging from large scale genetics to clinical interventions. These expert reviews are followed by a collection of papers intended to illustrate new or underrepresented methods in our field and include novel approaches to clinical trials to the quantification of text data collected from public repositories online. The issue concludes with a number of original data papers applying network analysis to study comorbidity and symptom status in eating disorder and related populations and a couple of novel neuroimaging papers demonstrating the use of new and promising methods for studying heterogeneity and the use of psychophysiology to answer questions about emotion in eating disorder populations.
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