[Airway obstruction due to localized tracheal lesion of extranodal NK/T-cell lymphoma, nasal type]

Rinsho Ketsueki. 2018;59(8):1012-1015. doi: 10.11406/rinketsu.59.1012.
[Article in Japanese]

Abstract

A 76-year-old man presented with a tracheal tumor associated with severe respiratory obstruction. A tracheotomy was performed due to respiratory failure. F-fluorodeoxyglucose (FDG) -positron emission tomography/computed tomography revealed an abnormal accumulation of FDG (maximum standardized uptake value: 16) in the trachea. A histopathological examination of the tracheal biopsy revealed extranodal NK/T-cell lymphoma, nasal type (ENKL). He was treated with concurrent radiotherapy (50 Gy) for the tracheal tumor and three courses of two-thirds dose ofdexamethasone, etoposide, ifosfamide, and carboplatin. Although the tumor responded remarkably well to this therapy, the patient died of an ENKL recurrence in the lungs and liver 11 months post therapy.

Keywords: Extranodal NK/T-cell lymphoma; RT-2/3DeVIC; nasal type; respiratory failure; trachea; acute.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Airway Obstruction*
  • Fatal Outcome
  • Fluorodeoxyglucose F18
  • Humans
  • Lymphoma, Extranodal NK-T-Cell / pathology*
  • Lymphoma, Extranodal NK-T-Cell / therapy
  • Male
  • Positron Emission Tomography Computed Tomography
  • Trachea / pathology*

Substances

  • Fluorodeoxyglucose F18