Calcification of the intervertebral disc and ossification of posterior longitudinal ligament in children

BMC Musculoskelet Disord. 2018 Sep 5;19(1):316. doi: 10.1186/s12891-018-2227-z.

Abstract

Background: IDC in children, first reported by Baron in 1924, is very rare. OPLL of the cervical spine mainly affect people ages 50-70 years. The coexistence of IDC and OPLL in children is very rare, only six cases with 3 to 24 months' follow-up were reported to date.

Case presentation: A 6-year-old boy presented with complains of neck pain at July 2007. The boy was treated by conservative treatment and observed up for 9 years. Neck pain greatly improved after a one-month conservative treatment and never recur. Laboratory tests revealed elevated ESR and CRP at admission and found nothing abnormal at 19-month and 9-year follow-up. Computed tomography and magnetic resonance imaging revealed IDC at C2/3, C3/4 and OPLL at C3/4 at admission and found minor calcification at C2/3 remained but calcification at C3/4 and OPLL at C3/4 completely disappeared at 19-month and 9-year follow-up. Nineteen months after initial diagnosis, restoration of T2-weighted signal intensity of C2/3 and C3/4 discs was observed through MRI. Loss of T2-weighted signal intensity of C2/3 disc and decrease of T2-weighted signal intensity of C3/4 disc was observed at 9-year follow-up.

Conclusions: IDC with OPLL in children is very rare. Conservative treatments are recommended with affirmative short-term and long-term clinical effects. More intensive observation with long-term follow-ups may be needed to warrant the clinical effects.

Keywords: Cervical spine; Intervertebral disc calcification; Ossification of the posterior longitudinal ligament; Pediatric.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Calcinosis / complications*
  • Calcinosis / diagnostic imaging*
  • Calcinosis / therapy
  • Cervical Vertebrae / diagnostic imaging*
  • Child
  • Conservative Treatment
  • Humans
  • Male
  • Neck Pain / diagnostic imaging
  • Neck Pain / etiology
  • Neck Pain / therapy
  • Ossification of Posterior Longitudinal Ligament / complications*
  • Ossification of Posterior Longitudinal Ligament / diagnostic imaging*
  • Ossification of Posterior Longitudinal Ligament / therapy