Successful treatment of giant condyloma in a pediatric heart transplant recipient with topical cidofovir

Transpl Infect Dis. 2018 Dec;20(6):e12989. doi: 10.1111/tid.12989. Epub 2018 Sep 28.

Abstract

We report a case of giant condyloma that developed in a pediatric heart transplant recipient. This infection progressed for several months despite reduction in immunosuppression, topical treatment, and oral cimetidine therapy. Complete resolution was observed following 7 months of topical cidofovir, without evidence of systemic toxicity or rejection.

Keywords: cidofovir; condyloma acuminata; human papilloma virus; immunocompromised; pediatrics; solid organ transplant.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use*
  • Buschke-Lowenstein Tumor / diagnostic imaging
  • Buschke-Lowenstein Tumor / drug therapy*
  • Buschke-Lowenstein Tumor / pathology
  • Buschke-Lowenstein Tumor / virology
  • Child, Preschool
  • Cidofovir / therapeutic use
  • Female
  • Heart Transplantation / adverse effects*
  • Human papillomavirus 6 / isolation & purification
  • Humans
  • Immunosuppression Therapy / adverse effects
  • Immunosuppression Therapy / methods
  • Photography
  • Skin / pathology
  • Skin / virology
  • Skin Neoplasms / diagnostic imaging
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / virology
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Cidofovir