The Comorbidity of Focal Epilepsy and Narcolepsy Type 1 - Two Case Reports

Neuro Endocrinol Lett. 2018 May;39(2):95-98.

Abstract

The aim of this study is to remind the possibility of co-occurrence of epilepsy and narcolepsy. In the first case report, narcolepsy type 1 was diagnosed in 29-year-old female. After one year of the treatment with modafinil a new episodes of automatic behavior appeared. Patient was reevaluated and the diagnosis of focal epilepsy with partial complex seizures was established. Patient was treated with modafinil and lamotrigine and became seizure-free. In the second case report a 21-year-old female was referred with a typical history of narcolepsy type 1, but also with atypical episodes of gazing and automatic behavior with amnesia for these episodes. Narcolepsy type 1 and focal epilepsy was diagnosed. Some clinical symptoms of narcolepsy (cataplexy, automatic behavior, episodes of sleep attacks) need to be carefully analyzed by EEG and video-EEG not to overlook the epilepsy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Amnesia / etiology
  • Amnesia / psychology
  • Anticonvulsants / therapeutic use
  • Behavior
  • Central Nervous System Stimulants / therapeutic use
  • Electroencephalography
  • Epilepsies, Partial / complications*
  • Epilepsies, Partial / psychology
  • Female
  • Humans
  • Lamotrigine / therapeutic use
  • Modafinil / therapeutic use
  • Narcolepsy / complications*
  • Narcolepsy / drug therapy
  • Narcolepsy / psychology
  • Treatment Outcome
  • Young Adult

Substances

  • Anticonvulsants
  • Central Nervous System Stimulants
  • Modafinil
  • Lamotrigine