Hypomethylation, endogenous retrovirus expression, and interferon signaling in testicular germ cell tumors

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8580-E8582. doi: 10.1073/pnas.1803292115. Epub 2018 Sep 4.

Authors

Michael C Haffner^{1

2}, Diana Taheri², Eddie Luidy-Imada³, Doreen N Palsgrove², Marie-Lisa Eich², George J Netto^{3

2

4}, Andres Matoso^{3

2}, Thomas R Nirschl³, Qizhi Zheng², Jessica L Hicks², William G Nelson^{3

2

4}, Angelo M De Marzo^{3

2

4}, Luigi Marchionni^{3

2}, Charles G Drake⁵, Srinivasan Yegnasubramanian^{1

2}

Affiliations

¹ Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21218; mhaffne4@jhmi.edu syegnasu@jhmi.edu.
² Department of Pathology, Johns Hopkins University, Baltimore, MD 21218.
³ Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21218.
⁴ Brady Urological Institute, School of Medicine, Johns Hopkins University, Baltimore, MD 21218.
⁵ Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Endogenous Retroviruses*
Humans
Interferons
Male
Neoplasms, Germ Cell and Embryonal
Testicular Neoplasms / genetics*

Substances

Interferons

Supplementary concepts

Testicular Germ Cell Tumor

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