Dietary Inflammatory Index and clinical course of multiple sclerosis

Eur J Clin Nutr. 2019 Jul;73(7):979-988. doi: 10.1038/s41430-018-0294-8. Epub 2018 Sep 3.

Abstract

Objectives: This study aims at analyzing the association between the Dietary Inflammatory Index (DII) and the clinical condition of multiple sclerosis (MS) patients.

Methods: It is a quantitative, cross-sectional analytical study that included 137 MS patients assisted at a reference center for MS treatment in the Brazilian northeast. Data was collated through a structured questionnaire and medical records consultation, also involving demographic, clinical, and nutritional variables. Clinical variables included the MS type, diagnosis and follow-up start dates, investigation of recent urinary tract symptoms, use of immunomodulatory, vitamin D supplementation, number of recent pulse therapies, relapse rate in the last 2 years, muscular strength assessment (MRC), disability degree (EDSS), and a gadolinium-enhanced magnetic resonance imaging (MRI) scan in the central white matter (CWM). The DII was calculated according to the Shivappa et al. methodology.

Results: There was no difference in any of the variables according to the DII (p > 0.05).

Conclusions: The Dietary Inflammatory Index did not affect the clinical condition of individuals with multiple sclerosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Brazil
  • Cross-Sectional Studies
  • Diet*
  • Female
  • Humans
  • Inflammation*
  • Male
  • Multiple Sclerosis / immunology*
  • Recurrence
  • Severity of Illness Index*
  • Socioeconomic Factors