The use of nanoparticles as biomaterials in dentistry

Drug Discov Today. 2019 Jan;24(1):85-98. doi: 10.1016/j.drudis.2018.08.012. Epub 2018 Aug 31.

Abstract

Maintenance of oral health is a major challenge in dentistry. Different materials have been used to treat various dental diseases, although treatment success is limited by features of the biomaterials used. To overcome these limitations, materials incorporated with nanoparticles (NPs) can be used in dental applications including endodontics, periodontics, tissue engineering, oral surgery, and imaging. The unique properties of NPs, including their surface:volume ratio, antibacterial action, physical, mechanical, and biological characteristics, and unique particle size have rendered them effective vehicles for dental applications. In this review, we provide insights into the various applications of NPs in dentistry, including their benefits, limitations, properties, actions and future potential.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biocompatible Materials / therapeutic use*
  • Dentistry
  • Humans
  • Nanoparticles / therapeutic use*

Substances

  • Biocompatible Materials