Helminth extracellular vesicles in host-parasite interactions

Curr Opin Microbiol. 2018 Dec:46:73-79. doi: 10.1016/j.mib.2018.08.002. Epub 2018 Aug 30.

Abstract

Extracellular vesicles (EVs) have been characterized from many species of parasitic helminths, and recent experimental evidence supports important functions for their cargo in host-parasite relationships as immunomodulatory mediators. Here we summarize available data on the effects of parasite-derived EVs, including their protein and/or small RNA contents, on their hosts.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Extracellular Vesicles / genetics
  • Extracellular Vesicles / metabolism*
  • Helminthiasis / parasitology*
  • Helminthiasis / physiopathology
  • Helminths / genetics
  • Helminths / metabolism*
  • Host-Parasite Interactions*
  • Humans