Utility of short-interval follow-up mammography after a benign-concordant stereotactic breast biopsy result

Breast. 2018 Dec:42:50-53. doi: 10.1016/j.breast.2018.08.101. Epub 2018 Aug 23.

Abstract

Background: There is currently no clear consensus recommendation for the use of short-interval follow-up mammography after a benign-concordant breast biopsy (BCBB), and practice patterns vary widely. The objectives of this study were to evaluate whether a short-interval follow-up mammogram provided clinical utility after stereotactic BCBB and to examine the costs associated with this surveillance strategy.

Methods: A retrospective review of women who underwent a stereotactic breast biopsy yielding benign-concordant results between January 2005 and October 2014 was performed to evaluate findings on subsequent imaging, to calculate compliance with recommended short-interval imaging, and to examine whether subsequent imaging revealed an abnormality at the site of the initial stereotactic BCBB. A cost analysis was performed utilizing Medicare reimbursement rates to calculate projected and actual costs of short-interval follow-up imaging after stereotactic BCBB.

Results: Of the 470 stereotactic BCBB performed, a short-interval mammogram was completed in 207 (44.0%), 9 (4.3%) of which had suspicious mammographic findings at the initial biopsy site, and 6 subsequently underwent biopsy, with none resulting in malignant or high-risk pathology. The cost of short-interval mammographic follow-up (n = 207) was calculated at $28,541.16.

Conclusions: This study provides evidence that 6-month follow-up mammography has low clinical utility and unnecessarily increases costs after stereotactic BCBB. A safe and more cost-effective strategy may be resumption of routine mammography at 12 months post-biopsy.

Keywords: Benign-concordant; Breast biopsy; Mammography follow-up; Recommendations; Stereotactic biopsy.

MeSH terms

  • Adult
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / economics
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Early Detection of Cancer / economics
  • Early Detection of Cancer / statistics & numerical data*
  • Female
  • Follow-Up Studies
  • Humans
  • Image-Guided Biopsy / economics
  • Image-Guided Biopsy / statistics & numerical data*
  • Mammography / economics
  • Mammography / statistics & numerical data*
  • Middle Aged
  • Neoplasm Staging
  • Prognosis
  • Retrospective Studies