Hybrid training system-induced myokine secretion in healthy men

Cytokine. 2018 Nov:111:178-181. doi: 10.1016/j.cyto.2018.08.023. Epub 2018 Aug 29.

Abstract

The hybrid training system (HTS) is a special and compact system for effective skeletal muscle training by a combined application of volitional and electrical muscle contraction. Lower limbs' muscle training using HTS has been reported to increase not only muscle strength but also plasma interleukin-6 levels; however, little is known in other cytokines. In this study, we measured 52 cytokines and creatine phosphokinase-MM in the serum of 16 healthy men before and after lower limbs' muscle training by the knee flexion and extension using HTS. Skeletal muscle volume-corrected serum concentrations of cutaneous T-cell-attracting chemokine, erythropoietin, and tumor necrosis factor-related apoptosis-inducing ligand increased immediately after the training. These increased cytokines have been reported to play important roles in wound healing, neuroprotection, and cardiovascular protection.

Keywords: CTACK; Erythropoietin; Myokine; TRAIL; Training.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Apoptosis / physiology
  • Chemokine CCL27 / metabolism
  • Cytokines / metabolism*
  • Erythropoietin / metabolism
  • Humans
  • Knee / physiology
  • Lower Extremity / physiology
  • Male
  • Muscle Contraction / physiology
  • Muscle Strength / physiology
  • Muscle, Skeletal / metabolism*
  • Tumor Necrosis Factor-alpha / metabolism

Substances

  • Chemokine CCL27
  • Cytokines
  • Tumor Necrosis Factor-alpha
  • Erythropoietin