Many naturally occurring biologically active compounds are derived from marine organisms. Brachyuran crab Dromia dehaani is also known as sponge crab. Hence, this study was undertaken to isolate and characterize the antimicrobial peptide from the marine crab hemolymph. Therefore the objectives of this research work was to high light the functions of biologically active peptide Dromidin. Dromidin was identified and confirmed as a new antimicrobial peptide in the hemolymph of the crab D. dehaani. Antimicrobial peptide was characterized and confirmed by using various analytical techniques. ESI-MS analysis of the active antimicrobial hemolymph fraction resulted in the value 513.0 Da. In addition, current findings strongly suggest that this peptide is functionally important against the pathogens.
Keywords: Antimicrobial; Biological activity; Dromia dehaani; Hemolymph; Peptide.
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