Objective: To investigate the relationship of the characteristics of sperm donors with the results of screening and provide some reference for the screening of sperm donors.
Methods: We statistically analyzed the screening data about 12 362 sperm donors at the Guangdong Human Sperm Bank from January 2003 to June 2017 and the relationship of the eligibility rate of screening with the donors' age, education, occupation, marriage, and fatherhood.
Results: Of the 12 362 sperm donors, 3 968 (32.1%) met the standards of semen quality and 3 127 (25.3%) filled all the requirements of sperm donation. The eligibility rate of screening was 27.7% in the donors aged 20－24 years, 24.3% in those aged 25－29 years, 23.8% in those aged 30－34 years, and 17.5% in those aged =≥35 years (P < 0.01); 23.5% in the senior high school students, 24% in the junior college students, 25.9% in the undergraduates, and 30.3% in the postgraduates (P < 0.01); 29.3% in the students versus 22.9% in the others (P < 0.01), 41.5% in the married versus 20.7% in the unmarried (P < 0.01), and 45.6% in the fathers versus 20.9% in the childless husbands (P < 0.01).
Conclusions: A higher eligibility rate of screening was found among the sperm donors aged <35 years or with a bachelor's or higher degree, particularly among students.
目的： 探讨捐精志愿者年龄、学历、职业、婚育特征与筛查结果的关系，为精子库捐精宣传招募工作提供参考。方法： 对广东精子库2003年1月至2017年6月期间12 362例捐精志愿者的筛查资料进行汇总统计，分析捐精志愿者年龄、学历、职业、婚育特征与筛查合格率的关系。结果：12 362例志愿者中，3 968例（32.1%）精液质量达到合格标准；全部检查结果达到精子库捐精标准即筛查合格的志愿者3 127例（25.3%）。志愿者达到精子库捐精标准合格率20~24岁组为27.7%，25~29岁组24.3%，30~34岁组23.8%，=≥35岁组17.5%，不同年龄组筛查合格率差异有统计学意义（P<0.01）。高中、专科、本科、研究生的志愿者筛查合格率分别为23.5%、24.0%、25.9%和30.3%，差异有统计学意义（P=0.000）。学生和社会人员的筛查合格率分别为29.3%和22.9%，差异有统计学意义（P<0.01）。已婚和未婚志愿者的筛查合格率分别为41.5%和20.7%，差异有统计学意义（P<0.01）。已生育和未生育志愿者的筛查合格率分别为45.6%和20.9%，差异有统计学意义（P<0.01）。结论： 人类精子库尽量招募年龄低于35岁、学历大学本科或以上并以学生为主的志愿者，并面向此类人群进行精准宣传，提高他们捐精的积极性和意愿，从而提高精子库筛查合格率。.
Keywords: characteristics; eligibility rate; screening; sperm bank; sperm donation.