Multiple isodicentric Y chromosomes in myeloid malignancies: a unique cytogenetic entity and potential therapeutic target

Leuk Lymphoma. 2019 Mar;60(3):821-824. doi: 10.1080/10428194.2018.1498492. Epub 2018 Aug 30.

Affiliations

¹ a Division of Hematology , Mayo Clinic , Rochester , MN, USA.
² b Department of Health Sciences Research , Mayo Clinic , Rochester , MN, USA.
³ c Department of Pathology and Laboratory Medicine , University of North Carolina , Chapel Hill, NC , USA.
⁴ d Department of Laboratory Medicine and Pathology , Mayo Clinic , Rochester , MN, USA.

PMID: 30160574
DOI: 10.1080/10428194.2018.1498492

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Aged, 80 and over
Biomarkers, Tumor
Bone Marrow / pathology
Chromosome Aberrations
Chromosomes, Human, Y*
Combined Modality Therapy
Cytogenetic Analysis
Gene Duplication*
Genetic Association Studies
Genetic Predisposition to Disease*
Humans
Leukemia, Myeloid / diagnosis*
Leukemia, Myeloid / genetics*
Leukemia, Myeloid / metabolism
Leukemia, Myeloid / therapy
Male
Middle Aged
Molecular Targeted Therapy
Treatment Outcome

Substances

Biomarkers, Tumor