Left inferior frontal cortex can compensate the inhibitory functions of right inferior frontal cortex and pre-supplementary motor area

J Neuropsychol. 2019 Sep;13(3):503-508. doi: 10.1111/jnp.12170. Epub 2018 Aug 29.

Abstract

Right-IFG and pre-SMA are associated with inhibitory responses. We used functional Magnetic Resonance Imaging to explore whether the contralateral homotopic regions can functionally replace them. An adolescent, with an extensive traumatic lesion of the right cerebral hemisphere having occurred 5 years earlier, performed a motor response inhibition task (Go/Nogo), which was properly accomplished and associated to activations in the left-IFC, precuneus and occipital cortex. Such functional remodelling is in line with the theory of 'near equipotentiality' of the cerebral hemispheres.

Keywords: Go Nogo; inhibition; l-IFC; pre-SMA; r-IFG.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brain Injuries, Traumatic / psychology
  • Child
  • Decompressive Craniectomy
  • Female
  • Functional Laterality*
  • Hematoma, Subdural / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Motor Cortex / diagnostic imaging
  • Motor Cortex / physiopathology*
  • Occipital Lobe / physiopathology
  • Parietal Lobe / physiopathology
  • Prefrontal Cortex / diagnostic imaging
  • Prefrontal Cortex / injuries
  • Prefrontal Cortex / physiopathology*
  • Psychomotor Performance
  • Suicide, Attempted
  • Ventriculoperitoneal Shunt